Assessment of cardiac radiation dose in the Co-60 prone-based stereotactic partial breast irradiation using distance metrics

Leveraging its sharp dose fall-off characteristic, the GP treatment delivery system facilitates the delivery of five-fraction APBI while maintaining acceptable cardiac dosimetry parameters. This is particularly advantageous for tumors situated further from the heart because heart doses dissipate with distance. The estimates of heart dose based on the distance to the heart and LAD from PTV have the potential to serve as a valuable tool for clinicians, aiding in more refined risk evaluation and patient selection for CP-sPBI.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-09-04
DOI
https://doi.org/10.3389/fonc.2025.1458111
Primary Topic
Breast Cancer Treatment Studies
Type
article
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article

Assessment of cardiac radiation dose in the Co-60 prone-based stereotactic partial breast irradiation using distance metrics

Asal Rahimi, Xingzhe Li, Mu‐Han Lin, You Zhang et al.
1 links
Frontiers in Oncology
Breast Cancer Treatment Studies
article

Assessment of cardiac radiation dose in the Co-60 prone-based stereotactic partial breast irradiation using distance metrics

Asal Rahimi, Xingzhe Li, Mu‐Han Lin, You Zhang, Tsuicheng Chiu, Yesenia Gonzalez, Prasanna Alluri, Mona Arbab, Xuejun Gu, David Parsons, Weiguo Lu, Strahinja Stojadinović, Narine Wandrey, D. Kim, Li‐Yuan Chen, Young Suk Kwon, Robert Timmerman, Prashant Yarlagadda
article en

Abstract

Leveraging its sharp dose fall-off characteristic, the GP treatment delivery system facilitates the delivery of five-fraction APBI while maintaining acceptable cardiac dosimetry parameters. This is particularly advantageous for tumors situated further from the heart because heart doses dissipate with distance. The estimates of heart dose based on the distance to the heart and LAD from PTV have the potential to serve as a valuable tool for clinicians, aiding in more refined risk evaluation and patient selection for CP-sPBI.

Frontiers in OncologyVol. 15
Palo Alto University (US), The University of Texas Southwestern Medical Center (US), Vanderbilt University Medical Center (US), Stanford University (US)
Openalex Percentile: Top 71%
Breast Cancer Treatment Studies
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