Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial–mesenchymal transition
These confirmed that ISO inhibits the EMT of renal tubular epithelial cells by suppressing the TWEAK/Fn14 signaling pathway.
Authors
- Wenhao Luo (ORCID: https://orcid.org/0000-0001-9914-5338)
- Zhihui Chen (ORCID: https://orcid.org/0000-0002-2934-7505)
- Lihong Nan
- Wen Xu (ORCID: https://orcid.org/0000-0002-2327-0332)
- Zixin Chen
- Weihua Peng (ORCID: https://orcid.org/0000-0003-3380-6409)
- Lijuan Xiao (ORCID: https://orcid.org/0000-0002-8647-8296)
- Haiwei Guan (ORCID: https://orcid.org/0009-0007-4113-2615)
- Ya Lin (ORCID: https://orcid.org/0000-0002-9361-2190)
- Yuqin Zhang (ORCID: https://orcid.org/0000-0002-4872-0889)
- Yaping Chen (ORCID: https://orcid.org/0000-0001-6748-7448)
- Mei Huang (ORCID: https://orcid.org/0000-0002-3333-1784)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fuzhou Second Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fimmu.2025.1649327
- Citations
- 1
- Primary Topic
- Connective Tissue Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Fujian University of Traditional Chinese Medicine