Association of systemic inflammatory factors with clinical outcomes in patients with autoimmune encephalitis at different clinical stages
SII and PLR were associated with disease severity, while NPR was a consistent predictor of poor long-term outcomes. These findings highlight the value of systemic inflammatory factors in monitoring disease progression and guiding treatment decisions in patients with AE mediated by cell surface antibody.
Authors
- Wenxin Wu (ORCID: https://orcid.org/0000-0001-6333-6773)
- Yiqun Duan
- Thandar Aung (ORCID: https://orcid.org/0000-0002-6770-9642)
- Huadong Wu (ORCID: https://orcid.org/0000-0002-6315-6278)
- Bo Jin (ORCID: https://orcid.org/0000-0003-3912-6156)
- Sheng Zhang (ORCID: https://orcid.org/0000-0002-6818-0330)
- Xiaoyan Wu (ORCID: https://orcid.org/0000-0002-7720-4373)
- Jing Hu
Institutions
- Sir Run Run Shaw Hospital (CN)
- University of Pittsburgh Medical Center (US)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fimmu.2025.1632690
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province