Indian Interventional Cardiologists’ Perspectives on De-escalating Dual to Single Antiplatelet Therapy in High Bleeding Risk (HBR) Patients

This study presents Indian interventional cardiologists' perspectives on de-escalation strategies, including transitioning from DAPT to SAPT, to reduce bleeding complications, while ensuring adequate ischemic protection in patients with HBR post-PCI. Interventional cardiologists have outlined criteria for identifying critical HBR factors relevant to the Indian population. Clopidogrel was the most preferred medication for transitioning to SAPT in HBR patients. Simplified Indian bleeding risk scoring tools and tailored approaches are essential for improving DAPT management in patients with HBR.

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Publication Details

Journal
Cureus
Published
2025-09-03
DOI
https://doi.org/10.7759/cureus.91568
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Indian Interventional Cardiologists’ Perspectives on De-escalating Dual to Single Antiplatelet Therapy in High Bleeding Risk (HBR) Patients

Abraham Oomman, Ankita Chitre, Jagdish C. Mohan, Saumitra Ray et al.
Cureus
Antiplatelet Therapy and Cardiovascular Diseases
article

Indian Interventional Cardiologists’ Perspectives on De-escalating Dual to Single Antiplatelet Therapy in High Bleeding Risk (HBR) Patients

Abraham Oomman, Ankita Chitre, Jagdish C. Mohan, Saumitra Ray, B. Nath, Shah Vt
article en

Abstract

This study presents Indian interventional cardiologists' perspectives on de-escalation strategies, including transitioning from DAPT to SAPT, to reduce bleeding complications, while ensuring adequate ischemic protection in patients with HBR post-PCI. Interventional cardiologists have outlined criteria for identifying critical HBR factors relevant to the Indian population. Clopidogrel was the most preferred medication for transitioning to SAPT in HBR patients. Simplified Indian bleeding risk scoring tools and tailored approaches are essential for improving DAPT management in patients with HBR.

CureusVol. 17(9)
Apollo Hospitals (IN), Ajanta Pharma (India) (IN), Surya Hospitals (IN), Jaipur Golden Hospital (IN), Apollo Hospitals (IN), Apollo Hospitals (IN), Manipal Hospital (IN)
Openalex Percentile: Top 63%
Antiplatelet Therapy and Cardiovascular Diseases
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