Weight loss interventions and obesity‐associated cancers in people with type 2 diabetes and overweight/obesity: A real‐world observational study
Semaglutide and BS were associated with lower cancer rates in individuals with overweight/obesity and T2D, with non-significant lower rates also observed with tirzepatide. These findings suggest weight-loss interventions may contribute to cancer prevention in this population.
Authors
- Dimitris Papamargaritis (ORCID: https://orcid.org/0000-0001-5044-1515)
- Thomas J. Wilkinson (ORCID: https://orcid.org/0000-0002-7855-7752)
- Thomas E. Yates (ORCID: https://orcid.org/0000-0002-5724-5178)
- Karen Brown (ORCID: https://orcid.org/0000-0002-5217-1501)
- Jonathan Goldney (ORCID: https://orcid.org/0000-0001-8553-8296)
- Francesco Zaccardi (ORCID: https://orcid.org/0000-0002-2636-6487)
- Melanie Jane Davies (ORCID: https://orcid.org/0000-0002-9987-9371)
- Testimony Ipaye
Institutions
- University of Leicester (GB)
- Leicester General Hospital (GB)
- University Hospitals of Leicester NHS Trust (GB)
- NIHR Leicester Biomedical Research Centre (GB)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1111/dom.70090
- Citations
- 2
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- University of Leicester
- NIHR Leicester Biomedical Research Centre