Impact of platelet transfusions on plasma proteomes in controlled endotoxemia and in hemato‐oncological patients
Platelet transfusions did not induce specific quantitative changes in plasma protein levels in healthy volunteers. Nonetheless, they were associated with increased levels of PPBP in hemato-oncological patients. In general, no evidence of inflammation or other dysregulated processes was observed following platelet transfusions.
Authors
- Stefan F. van Wonderen (ORCID: https://orcid.org/0000-0002-4923-2289)
- Anna L. Peters (ORCID: https://orcid.org/0000-0003-0327-1378)
- Paula F. Ypma (ORCID: https://orcid.org/0000-0003-1250-7979)
- Diana Mūnoz Sandoval (ORCID: https://orcid.org/0000-0001-8350-3989)
- Pieter F. van der Meer (ORCID: https://orcid.org/0000-0002-2093-3604)
- Floor L. F. van Baarle (ORCID: https://orcid.org/0000-0003-4921-8820)
- Jan Voorberg (ORCID: https://orcid.org/0000-0003-4585-2621)
- Alexander P. J. Vlaar (ORCID: https://orcid.org/0000-0002-3453-7186)
- Isabella Viegen
- Jean‐Louis H. Kerkhoffs
- Eva R. Smit (ORCID: https://orcid.org/0009-0008-2001-1205)
- Maartje van den Biggelaar
Institutions
- Sanquin (NL)
- Amsterdam Neuroscience (NL)
- Haga Hospital (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Transfusion
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1111/trf.18397
- Citations
- 1
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- ZonMw
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Stichting Sanquin Bloedvoorziening