From Anesthetic to Neuroprotector: Multi-Omics Reveals Ketamine's Previously Unexplored Neuroprotective Role in Alzheimer's Disease
This integrative study identifies robust diagnostic biomarkers and nominates ketamine for repurposing in AD. Experimental validation of ketamine's neuroprotective effects and FIBP's role is warranted.
Authors
- Wenlong Du (ORCID: https://orcid.org/0000-0003-2526-5278)
- Xiaodong Xu (ORCID: https://orcid.org/0000-0002-6473-6637)
- Yu Tian (ORCID: https://orcid.org/0000-0002-5997-1456)
- Yan Zhou
- Yan Zhu (ORCID: https://orcid.org/0009-0002-1871-1380)
- Yue Gong
Institutions
- Xuzhou Medical College (CN)
- Second Affiliated Hospital of Xuzhou Medical College (CN)
- Xuzhou No.1 People's Hospital (CN)
Publication Details
- Journal
- CNS & Neurological Disorders - Drug Targets
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2174/0118715273396403250825131703
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00