Effectiveness of infection control measures informed by a modified Blue-Carba test in reducing rectal carriage of carbapenemase-producing bacteria in general wards: a prospective interrupted time series study
The implementation of the NA reduced mTAT with high sensitivity, while the mBCT also contributed to reducing TPR with high specificity. Integrating the NA and mBCT into IPC protocols led to a decrease in CPB rectal carriage prevalence in general wards, underscoring their diagnostic, epidemiological and thus IPC benefits.
Authors
- Corrado Bernasconi (ORCID: https://orcid.org/0000-0002-1019-5468)
- Joaquín Ignacio Coduri Anthonioz Blanc (ORCID: https://orcid.org/0000-0001-8139-7641)
- Fernando Pasterán (ORCID: https://orcid.org/0000-0001-5840-5869)
- Maximiliano Gabriel Castro (ORCID: https://orcid.org/0000-0003-0112-8455)
- María José Sadonio (ORCID: https://orcid.org/0000-0003-1256-4754)
- Federico Rafael Galluccio
- Macarena Vicino (ORCID: https://orcid.org/0000-0001-7742-0191)
- Sonia Gómez (ORCID: https://orcid.org/0000-0001-9106-1762)
- Elsa Rottoli
- A. Amato (ORCID: https://orcid.org/0009-0009-4695-1833)
- Fernanda Argarañá
- Héctor Mario Musacchio
- Leticia Margenet
- Manuel Protto
Institutions
- Universidad Nacional del Litoral (AR)
- Centro Científico Tecnológico - Santa Fe (AR)
- Administración Nacional de Laboratorios e Institutos de Salud (AR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fphar.2025.1584646
- Citations
- 1
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- Fundación Florencio Fiorini
- Directorate for Biological Sciences
- Agencia Nacional de Promoción Científica y Tecnológica