Multi-transcriptomics analysis of ferroptosis related genes reveals CAFs exosomal COX4I2 as a novel therapeutic target in osteosarcoma
These findings underscore the potential of exosomal COX4I2 as a biomarker and therapeutic target for ferroptosis-based interventions in osteosarcoma.
Authors
- Zhongyi Li (ORCID: https://orcid.org/0000-0001-9365-0325)
- Xiaoying Niu (ORCID: https://orcid.org/0000-0001-9846-3844)
- Xinxin Zhang
- Wen Tian (ORCID: https://orcid.org/0000-0002-3046-4004)
Institutions
- Zhengzhou University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fcell.2025.1620648
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00