Clinical and pathological characteristics of NELL-1-positive membranous nephropathy: a case series study

NELL-1-positive MN is characterized by high rates of IgG1 and IgG4 deposition and generally favorable responses to therapy. A substantial proportion of patients were diagnosed with malignancy, highlighting the importance of cancer screening in this population. Timely identification and management of underlying malignancy may contribute to improved renal outcomes.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-09-04
DOI
https://doi.org/10.3389/fmed.2025.1615855
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical and pathological characteristics of NELL-1-positive membranous nephropathy: a case series study

K Li, Xiaojing Liu, Liang Zheng, Sanjie Cao
Frontiers in Medicine
Renal Diseases and Glomerulopathies
article

Clinical and pathological characteristics of NELL-1-positive membranous nephropathy: a case series study

K Li, Xiaojing Liu, Liang Zheng, Sanjie Cao
article en

Abstract

NELL-1-positive MN is characterized by high rates of IgG1 and IgG4 deposition and generally favorable responses to therapy. A substantial proportion of patients were diagnosed with malignancy, highlighting the importance of cancer screening in this population. Timely identification and management of underlying malignancy may contribute to improved renal outcomes.

Frontiers in MedicineVol. 12
Cangzhou Central Hospital (CN)
Openalex Percentile: Top 74%
Renal Diseases and Glomerulopathies
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