The first case of peritoneal dialysis-associated peritonitis caused by Gordonia otitidis

Abstract Background Gordonia spp. is a rare infectious disease that has been reported in only 18 cases to date as a cause of peritoneal dialysis-related peritonitis. This is the first report of peritonitis associated with peritoneal dialysis caused by Gordonia otitidis and is a valuable case in which long-term intravenous vancomycin administration was successful. Case presentation A 48-year-old female started peritoneal dialysis at the age of 47 years owing to end-stage renal failure caused by chronic glomerulonephritis. She was hospitalized for peritonitis 3 months after the start of dialysis. We administered cefazolin and ceftazidime intravenously and detected Gordonia otitidis in the drainage fluid after long-term culture for approximately 6 days. Therefore, we switched to vancomycin and treated the patient intravenously for a total of 6 weeks while checking blood levels and trough values in the drainage fluid. The patient had an increase in the number of draining cells for 3 weeks after the start of treatment, but the number of draining cells improved after that, and no relapse was observed 6 months after the end of treatment, suggesting that the treatment was successful. Conclusions When encountering peritoneal dialysis-associated peritonitis for the Gordonia genus, long-term intravenous administration of vancomycin should be considered as one of the treatments.

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Publication Details

Journal
Renal Replacement Therapy
Published
2025-09-04
DOI
https://doi.org/10.1186/s41100-025-00661-4
Primary Topic
Actinomycetales infections and treatment
Type
article
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article

The first case of peritoneal dialysis-associated peritonitis caused by Gordonia otitidis

Tomoaki Miyazaki, Kei Matsumoto, Shugo Aoki, Akiko Takeshima
Renal Replacement Therapy
Actinomycetales infections and treatment
article

The first case of peritoneal dialysis-associated peritonitis caused by Gordonia otitidis

Tomoaki Miyazaki, Kei Matsumoto, Shugo Aoki, Akiko Takeshima
article en

Abstract

Abstract Background Gordonia spp. is a rare infectious disease that has been reported in only 18 cases to date as a cause of peritoneal dialysis-related peritonitis. This is the first report of peritonitis associated with peritoneal dialysis caused by Gordonia otitidis and is a valuable case in which long-term intravenous vancomycin administration was successful. Case presentation A 48-year-old female started peritoneal dialysis at the age of 47 years owing to end-stage renal failure caused by chronic glomerulonephritis. She was hospitalized for peritonitis 3 months after the start of dialysis. We administered cefazolin and ceftazidime intravenously and detected Gordonia otitidis in the drainage fluid after long-term culture for approximately 6 days. Therefore, we switched to vancomycin and treated the patient intravenously for a total of 6 weeks while checking blood levels and trough values in the drainage fluid. The patient had an increase in the number of draining cells for 3 weeks after the start of treatment, but the number of draining cells improved after that, and no relapse was observed 6 months after the end of treatment, suggesting that the treatment was successful. Conclusions When encountering peritoneal dialysis-associated peritonitis for the Gordonia genus, long-term intravenous administration of vancomycin should be considered as one of the treatments.

Renal Replacement TherapyVol. 11(1)
Koto Hospital (JP)
Openalex Percentile: Top 73%
Actinomycetales infections and treatment
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