Direct-acting antiviral treatment significantly shaped the gut microbiota in chronic hepatitis C patients: a pilot study
DAAs have a significant impact on the gut microbiota in CHC patients, resulting in distinct microbial patterns, biomarkers, and interactions. Successful HCV eradication restores bacterial diversity and reestablishes microbial communities resembling those in healthy individuals.
Authors
- Mohammed Ramadan (ORCID: https://orcid.org/0000-0002-4577-0418)
- Mohamed S. Abdel‐Maksoud
- Elham Ahmed Hassan (ORCID: https://orcid.org/0000-0003-2575-758X)
- Hossam Mahmoud Abdelwahab
- Omnia M. Kamal El-Din (ORCID: https://orcid.org/0000-0002-2092-2411)
- Hashim M. Aljohani (ORCID: https://orcid.org/0000-0001-5333-6956)
- Nahla M. Elsherbiny (ORCID: https://orcid.org/0000-0002-5431-6583)
- Helal F. Hetta (ORCID: https://orcid.org/0000-0001-8541-7304)
- Mostafa A. Sayed Ali (ORCID: https://orcid.org/0000-0002-5851-5088)
- Mohamed S. Badary
- Roba Alatawy (ORCID: https://orcid.org/0000-0003-1514-3349)
- Zienab Gaber Mahran
- Marwa Abo Kresha
- Khaled Abo Bakr
- Fawaz E. Alanzai
Institutions
- Al-Azhar University (EG)
- Taibah University (SA)
- University of Tabuk (SA)
- Assiut University (EG)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fmicb.2025.1664447
- Citations
- 5
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 6.61