Copper Ferrite Nanoparticles: An Efficient Catalyst for the On e-Pot Four-Component Synthesis of Pyrano[2, 3-c] Pyrazole Derivatives

An efficient CuFe2O4 nanocatalyst was created using the simple and cost-effective assisted sol gel method, which has been effectively worked with as an efficient catalyst for one-pot multicomponent synthesis of pyrano[2,3-c] pyrazoles starting from aromatic aldehydes, malononitrile, ethyl acetoacetate, and hydrazine hydrate. The synthesized catalyst was characterized by using Fourier transform infrared (FT-IR), X-ray diffraction (XRD), energy dispersive X-ray (EDX), scanning electron microscopy (SEM), and transmission electron microscope (TEM) techniques.. The synthesized organic compounds were examined using IR, 1H NMR, and 13C NMR spectroscopy. The yield of pyrano[2,3-c] pyrazoles was studied using various reaction parameters such as the amount of catalyst, type of solvent, reaction conditions, and time. The present work's significant advantages such as simple setup, mild reaction conditions, non-toxic solvents, high yields, simple purification, efficiency, and utilization of recovered materials after four cycles.

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Journal
Letters in Organic Chemistry
Published
2025-09-04
DOI
https://doi.org/10.2174/0115701786394020250824114645
Primary Topic
Multicomponent Synthesis of Heterocycles
Type
article
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article

Copper Ferrite Nanoparticles: An Efficient Catalyst for the On e-Pot Four-Component Synthesis of Pyrano[2, 3-c] Pyrazole Derivatives

Anil Gadhave, Bhagwat K. Uphade, Amruta K. Mhaske, Sachin V. Patil
Letters in Organic Chemistry
Multicomponent Synthesis of Heterocycles
article

Copper Ferrite Nanoparticles: An Efficient Catalyst for the On e-Pot Four-Component Synthesis of Pyrano[2, 3-c] Pyrazole Derivatives

Anil Gadhave, Bhagwat K. Uphade, Amruta K. Mhaske, Sachin V. Patil
article en

Abstract

An efficient CuFe2O4 nanocatalyst was created using the simple and cost-effective assisted sol gel method, which has been effectively worked with as an efficient catalyst for one-pot multicomponent synthesis of pyrano[2,3-c] pyrazoles starting from aromatic aldehydes, malononitrile, ethyl acetoacetate, and hydrazine hydrate. The synthesized catalyst was characterized by using Fourier transform infrared (FT-IR), X-ray diffraction (XRD), energy dispersive X-ray (EDX), scanning electron microscopy (SEM), and transmission electron microscope (TEM) techniques.. The synthesized organic compounds were examined using IR, 1H NMR, and 13C NMR spectroscopy. The yield of pyrano[2,3-c] pyrazoles was studied using various reaction parameters such as the amount of catalyst, type of solvent, reaction conditions, and time. The present work's significant advantages such as simple setup, mild reaction conditions, non-toxic solvents, high yields, simple purification, efficiency, and utilization of recovered materials after four cycles.

Letters in Organic ChemistryVol. 23(2)
Department of Commerce (AU), Indian Numismatic, Historical and Cultural Research Foundation (IN)
Openalex Percentile: Top 82%
Multicomponent Synthesis of Heterocycles
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Copper Ferrite Nanoparticles: An Efficient Catalyst for the On e-Pot Four-Component Synthesis of Pyrano[2, 3-c] Pyrazole Derivatives — Anil Gadhave, Bhagwat K. Uphade, et al. · Letters in Organic Chemistry (2025) | TGRS Research Map | TGRS