Biodistribution and dosimetry of <sup>89</sup> Zirconium‐labeled microbiota transplants in the pig gut
The whole-body ED for L. crispatus and E. coli is lower than reported values for ingested tracers, such as that from <sup>89</sup>Zr labelled antibodies and <sup>111</sup>In labelled "meals" used to determine gut transit times. Hence ingestion of <sup>89</sup>Zr labelled bacteria shows promise for becoming a human nuclear-medicine procedure to determine the effectiveness of probiotic therapies.
Authors
- Heather Biernaski (ORCID: https://orcid.org/0000-0002-9018-3298)
- Gabriel Varela‐Mattatall (ORCID: https://orcid.org/0000-0001-6101-7218)
- Michael S. Kovacs (ORCID: https://orcid.org/0000-0003-0123-1356)
- Jonathan D. Thiessen (ORCID: https://orcid.org/0000-0001-6132-3020)
- Donna E. Goldhawk (ORCID: https://orcid.org/0000-0001-7285-8071)
- Frank S. Prato (ORCID: https://orcid.org/0000-0002-4592-2522)
- J.M. Schellenberg
- Neil Gelman
- Sarah C. Donnelly
- Mojmı́r Suchý (ORCID: https://orcid.org/0000-0001-5352-7592)
- Praveen Dassanayake (ORCID: https://orcid.org/0000-0002-5989-4921)
- Lela Deans
- Matthew S. Fox (ORCID: https://orcid.org/0000-0002-5121-4661)
- Jeremy P. Burton (ORCID: https://orcid.org/0000-0002-3591-6436)
- R. Terry Thompson
- Diksha Diksha
- Qin Sun (ORCID: https://orcid.org/0009-0009-8208-145X)
- Gerald Moran
- Yvonne Huston
- Dianne Bartolome
- Shaena Furlong
Institutions
- Western University (CA)
- Lawson Health Research Institute (CA)
- Siemens (Canada) (CA)
- CancerCare Manitoba (CA)
- University of Manitoba (CA)
- The University of Winnipeg (CA)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/mp.18087
- Citations
- 1
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 1.40