Bilateral Oculomotor Nerve Palsy: A Rare Complication of Bridging Thrombolysis for Acute Basilar Artery Occlusion

Acute vertebrobasilar artery occlusion (AVBAO) accounts for only 1-2% of ischemic stroke, but it has high disability and mortality rates. Mechanical thrombectomy (MT) combined with intravenous thrombolysis can quickly achieve vascular recanalization and significantly improve patient prognosis. This report describes a 73-year-old male who was admitted to the hospital in a coma due to AVBAO. After MT, successful recanalization of the basilar artery was achieved; however, the patient subsequently developed the rare but serious complication of bilateral oculomotor nerve palsy. The report emphasizes the need for careful preoperative planning, including detailed assessment of vascular anatomy and thrombus characteristics, and the importance of operator expertise. Improved intraoperative technique and close postoperative monitoring may help prevent complications such as vessel injury or embolic recurrence. Additionally, clinicians should be aware of the limitations of early DWI (Diffusion-weighted imaging) in detecting brainstem infarcts and of the need for clinical vigilance in the postoperative period.

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Journal
International Medical Case Reports Journal
Published
2025-09-01
DOI
https://doi.org/10.2147/imcrj.s532206
Primary Topic
Ophthalmology and Eye Disorders
Type
article
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article

Bilateral Oculomotor Nerve Palsy: A Rare Complication of Bridging Thrombolysis for Acute Basilar Artery Occlusion

Xin Guo, Jiapeng Sun, Hongmei Liu, S. Lv et al.
International Medical Case Reports Journal
Ophthalmology and Eye Disorders
article

Bilateral Oculomotor Nerve Palsy: A Rare Complication of Bridging Thrombolysis for Acute Basilar Artery Occlusion

Xin Guo, Jiapeng Sun, Hongmei Liu, S. Lv, Ronghui Liu, Cheng Ding
article en

Abstract

Acute vertebrobasilar artery occlusion (AVBAO) accounts for only 1-2% of ischemic stroke, but it has high disability and mortality rates. Mechanical thrombectomy (MT) combined with intravenous thrombolysis can quickly achieve vascular recanalization and significantly improve patient prognosis. This report describes a 73-year-old male who was admitted to the hospital in a coma due to AVBAO. After MT, successful recanalization of the basilar artery was achieved; however, the patient subsequently developed the rare but serious complication of bilateral oculomotor nerve palsy. The report emphasizes the need for careful preoperative planning, including detailed assessment of vascular anatomy and thrombus characteristics, and the importance of operator expertise. Improved intraoperative technique and close postoperative monitoring may help prevent complications such as vessel injury or embolic recurrence. Additionally, clinicians should be aware of the limitations of early DWI (Diffusion-weighted imaging) in detecting brainstem infarcts and of the need for clinical vigilance in the postoperative period.

International Medical Case Reports JournalVol. Volume 18
Huaian First People’s Hospital (CN)
Openalex Percentile: Top 66%
Ophthalmology and Eye Disorders
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