Detecting Cancer Early with Ultrasensitive Multimodal Liquid Biopsy
Wang and colleagues showed that ctDNA can be detected in plasma up to 3 years prior to clinical diagnosis. The study highlights the need for ultrasensitive and multimodal approaches that integrate the detection of mutations and copy-number changes with advanced computational platforms to deliver effective early-detection strategies. See related article by Wang et al., p. 1794.
Authors
- Giorgio Patelli (ORCID: https://orcid.org/0000-0001-8697-2158)
- Giovanni Crisafulli (ORCID: https://orcid.org/0000-0002-5511-1555)
- N. Saoudi Gonzalez (ORCID: https://orcid.org/0000-0001-6044-1703)
- Alberto Bardelli (ORCID: https://orcid.org/0000-0003-1647-5070)
Institutions
- University of Milan (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Vall d'Hebron Institut de Recerca (ES)
- IFOM (IT)
- University of Turin (IT)
Publication Details
- Journal
- Cancer Discovery
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1158/2159-8290.cd-25-1025
- Citations
- 2
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.87