The Effects of <scp>PLGA</scp> Nanoparticles Containing Different Growth Factors on Neural Stem Cell Differentiation and Their Transition Efficiency After Targeting With <scp>TRF</scp>
It is concluded that BDNF-PLGA-NPs, GDNF-PLGA-NPs, and TGF-ß3-PLGA-NPs are promising brain drug delivery carriers for NSC inducers, which could be useful in developing strategies for Parkinson's disease management, particularly when targeted with TRF.
Authors
- Gülçin Gacar (ORCID: https://orcid.org/0000-0003-2960-6826)
- Zehra Seda Halbutoğulları (ORCID: https://orcid.org/0000-0001-6810-4939)
- Sümeyye Narin (ORCID: https://orcid.org/0000-0003-4571-3728)
- Yusufhan Yazır (ORCID: https://orcid.org/0000-0002-8472-0261)
- Serap Mert (ORCID: https://orcid.org/0000-0001-5939-5295)
- Ayşegül Açıksarı
Institutions
- Sabancı Üniversitesi (TR)
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1111/cns.70576
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kocaeli Üniversitesi
- Sabancı Üniversitesi