Cisplatin-induced WWP1-eccDNA expression contributes to ovarian cancer resistance
WWP1-eccDNA is critical in OC resistance, with cisplatin treatment increasing WWP1-eccDNA levels, contributing to resistance. The ddPCR proves to be a superior method for eccDNA detection.
Authors
- Yi Tu (ORCID: https://orcid.org/0000-0002-2051-8806)
- Chenyang Lu
- Hui Zhang (ORCID: https://orcid.org/0000-0001-9692-3026)
- Kun Guo (ORCID: https://orcid.org/0000-0002-6270-2468)
- Rong Du (ORCID: https://orcid.org/0000-0001-8992-9956)
- Li Han (ORCID: https://orcid.org/0000-0002-4486-0534)
- Ruifang Li (ORCID: https://orcid.org/0000-0001-6974-7266)
- Xiang Guo (ORCID: https://orcid.org/0000-0003-1792-2071)
Institutions
- Henan University of Science and Technology (CN)
- Henan University of Technology (CN)
- Nanyang Institute of Technology (CN)
- Nanyang Medical College (CN)
Publication Details
- Journal
- Advances in Clinical and Experimental Medicine
- Published
- 2025-09-04
- DOI
- https://doi.org/10.17219/acem/204077
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Henan Province