Structure Elucidation and Complete NMR Spectral Assignments of New Sesquiterpenes Isolated From Marine Derived Fungus <scp> <i>Aspergillus sydowii</i> </scp> ‐HB
Six sesquiterpene derivative compounds (1-6), including one new 7R-sydowic acid (1) and five known compounds (2-6) were isolated from the secondary metabolites of Aspergillus sydowii-HB. The structures were determined by NMR spectroscopy and ESI-MS analysis, and the configuration of compound 1 was confirmed through DP4<sup>+</sup> calculation and NMR chemical shift. All the isolated compounds (1-6) were tested for their cytotoxic activities. The possible biosynthetic pathways for compounds (1-6) were also postulated.
Authors
- Baorui Teng
- Dan Zhang (ORCID: https://orcid.org/0000-0001-9651-8194)
- Hui Lei (ORCID: https://orcid.org/0000-0002-4757-586X)
- Siwei Chen (ORCID: https://orcid.org/0000-0003-1244-834X)
- Sijing Liu (ORCID: https://orcid.org/0000-0002-8375-4304)
- Xiujuan Fu (ORCID: https://orcid.org/0000-0003-2723-8169)
- Ya Yang
Institutions
- Southwest Medical University (CN)
- Deyang Stomatological Hospital (CN)
- Xian Yang Central Hospital (CN)
Publication Details
- Journal
- Magnetic Resonance in Chemistry
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1002/mrc.70035
- Citations
- 1
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.39