Correlation between AMH levels and embryonic aneuploidy rate in PGT-A patients: a retrospective study
In the PGT-A population, advanced maternal age (AMA), recurrent spontaneous abortion (RSA), or recurrent implantation failure (RIF) have been identified as contributing factors. After adjusting for potential confounders such as female age, AMH remains a significant risk factor for embryonic aneuploidy rates. The findings suggested that lower AMH levels are associated with a higher risk of embryonic aneuploidy, indicating that ovarian reserve function may be correlated with oocyte quality. These results provide new insights for individualized decision-making in assisted reproduction. Trial registration ChiCTR2500099710 (03/27/2025).
Authors
- Panpan Zhao (ORCID: https://orcid.org/0000-0001-7579-0033)
- Kaixuan Sun (ORCID: https://orcid.org/0000-0001-6586-1440)
- Qian Zhang (ORCID: https://orcid.org/0000-0002-0808-8794)
- Yuexin Yu (ORCID: https://orcid.org/0000-0002-2818-6092)
- Samuel Tang
Institutions
- Northern Hospital (AU)
- General Hospital of Shenyang Military Region (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1007/s10815-025-03619-x
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Key Research and Development Program of Liaoning Province