Unravelling symptom-specific polygenic effects on maternal mental health during the perinatal period and postpartum
Our findings highlight symptom-level associations between PGSs and maternal mental health, which may be obscured when global measures of mental health (e.g., overall scores) are used. Identifying symptom-specific PGS associations could advance current understanding of aetiological influences on maternal mental health.
Authors
- Giulia Piazza (ORCID: https://orcid.org/0000-0002-0117-7241)
- Jean‐Baptiste Pingault (ORCID: https://orcid.org/0000-0003-2557-4716)
- Omid V. Ebrahimi (ORCID: https://orcid.org/0000-0002-8335-2217)
- Ole A. Andreassen (ORCID: https://orcid.org/0000-0002-4461-3568)
- Helga Ask (ORCID: https://orcid.org/0000-0003-0149-5319)
- Alexandra Havdahl (ORCID: https://orcid.org/0000-0002-9268-0423)
- Robyn E. Wootton (ORCID: https://orcid.org/0000-0003-3961-3202)
- Laurie J. Hannigan (ORCID: https://orcid.org/0000-0003-3123-5411)
- Ludvig Daae Bjørndal (ORCID: https://orcid.org/0000-0001-9773-8287)
- Laura Hegemann (ORCID: https://orcid.org/0000-0002-7398-3760)
- Elizabeth C. Corfield (ORCID: https://orcid.org/0000-0002-0119-157X)
Institutions
- Oslo University Hospital (NO)
- Norwegian Institute of Public Health (NO)
- King's College London (GB)
- University of Bristol (GB)
- University of Oxford (GB)
- Lovisenberg Diakonale Høgskole (NO)
- Lovisenberg Diakonale Sykehus (NO)
- University College London (GB)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1016/j.jad.2025.120228
- Primary Topic
- Mental Health Research Topics
- Type
- article
- Field-Weighted Citation Impact
- 0.00