The Influence of Metabolic Dysfunction-Associated Steatotic Liver Disease and Body Mass Index on the Incidence of Alzheimer Disease: A Nationwide Cohort Study
A normal/underweight BMI and the presence of MASLD synergistically increased the risk of AD. The lean MASLD group had a higher risk of developing AD than the overweight/obese MASLD group, suggesting that the clinical relevance of MASLD for incident AD differs based on the BMI.
Authors
- Jimin Jeon (ORCID: https://orcid.org/0000-0003-1497-3914)
- Ja Kyung Kim (ORCID: https://orcid.org/0000-0001-5025-6846)
- Jinkwon Kim (ORCID: https://orcid.org/0000-0003-0156-9736)
- Tae Seop Lim (ORCID: https://orcid.org/0000-0002-4578-8685)
- Seok Jong Chung (ORCID: https://orcid.org/0000-0001-6086-3199)
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- University Health System (US)
- Yonsei University Health System (KR)
Publication Details
- Journal
- Gut and Liver
- Published
- 2025-09-04
- DOI
- https://doi.org/10.5009/gnl250079
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Yonsei University College of Medicine