Cytoskeleton Rearrangement Decreases Mitochondrial Fatty Acid Oxidation in Renal Tubular Epithelial Cells Contributing to Renal Fibrogenesis
These findings indicate that cytoskeleton stabilization is required to maintain TECs metabolism and that therapeutic manipulation of cytoskeleton remodeling could protect the kidney from fibrogenesis conditions.
Authors
- Brant G. Wang (ORCID: https://orcid.org/0000-0002-1329-1586)
- Yanjuan Hou (ORCID: https://orcid.org/0000-0002-5197-7394)
- E.H. Tan (ORCID: https://orcid.org/0000-0002-6370-2689)
- Yue Li (ORCID: https://orcid.org/0000-0002-4182-0588)
- Xiaojian Feng
- Songlin Niu
- Yu Wang (ORCID: https://orcid.org/0000-0003-3151-0778)
- Lihua Wang (ORCID: https://orcid.org/0000-0003-2741-7765)
- Xing Wan (ORCID: https://orcid.org/0000-0003-3667-3461)
- Huimin Niu
Institutions
- Shanxi Medical University (CN)
- Changzhi Medical College (CN)
- ShenZhen People’s Hospital (CN)
- Second Hospital of Shanxi Medical University (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/dddt.s520262
- Citations
- 1
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.32