Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors Versus Angiotensin Receptor Blockers: Multidatabase Target Trial Emulation Studies
This study suggests ACE inhibitor initiation was associated with higher risks of all-cause mortality and major adverse cardiovascular events compared with ARB initiation. These findings highlight the importance of carefully weighing the selection of angiotensin-aldosterone system inhibitors.
Authors
- Sheng Nie (ORCID: https://orcid.org/0000-0002-8267-7909)
- Chao Xie (ORCID: https://orcid.org/0000-0001-9489-5519)
- Yaduan Lin
- Licong Su (ORCID: https://orcid.org/0000-0002-3085-909X)
- Jiao Liu (ORCID: https://orcid.org/0000-0003-0304-241X)
- Fan Luo (ORCID: https://orcid.org/0009-0003-5048-543X)
- Shi-Yu Zhou (ORCID: https://orcid.org/0000-0002-8343-4810)
- Yaozhong Kong (ORCID: https://orcid.org/0000-0002-9178-6023)
- Ruixuan Chen (ORCID: https://orcid.org/0000-0002-2925-9484)
- L Y Chen
- Mingzhen Pang
- Zhixin Guo
Institutions
- Nanfang Hospital (CN)
- First People's Hospital of Foshan (CN)
- National Clinical Research (US)
- Southern Medical University (CN)
Publication Details
- Journal
- Hypertension
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25549
- Citations
- 3
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.16