EcoHIV Infection Promotes Atherosclerosis Progression in LDLR-Deficient Mice
Our data suggest that EcoHIV infection in <i>Ldlr</i><sup><i>-/-</i></sup> mice resembles the pathogenesis of atherosclerotic cardiovascular disease in people with HIV. Our findings have therapeutic implications for people with HIV, a vulnerable population with an elevated risk of cardiovascular disease.
Authors
- Eva Hu
- David J. Volsky (ORCID: https://orcid.org/0000-0001-6788-1752)
- Jaume Amengual
- Joan W. Berman (ORCID: https://orcid.org/0000-0003-0635-4072)
- Ivan Pinos (ORCID: https://orcid.org/0000-0002-2236-8936)
- Jennifer Kelschenbach (ORCID: https://orcid.org/0009-0007-8555-8378)
- Mike Veenstra
- Amparo Blanco (ORCID: https://orcid.org/0009-0000-8819-3131)
- Hongxia He
Institutions
- Albert Einstein College of Medicine (US)
- University of Illinois Urbana-Champaign (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1161/atvbaha.125.323004
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00