SIN-1 Improves Cerebral Blood Flow and Reduces Deviation From Brain Homeostasis During Ischemia and Reperfusion in Rats
SIN-1 emerges as a promising antihypertensive in acute stroke as it paradoxically increases rCBF in ischemic tissue and reduces no-reflow.
Authors
- Lina María Serna-Higuita (ORCID: https://orcid.org/0000-0001-5182-8295)
- Coline L. Lemâle (ORCID: https://orcid.org/0000-0001-8323-3296)
- Ingemar Fredriksson (ORCID: https://orcid.org/0000-0002-3454-6576)
- Baptiste Balança (ORCID: https://orcid.org/0000-0001-7917-9645)
- Jens P. Dreier (ORCID: https://orcid.org/0000-0001-7459-2828)
- Peter Martus (ORCID: https://orcid.org/0000-0002-5386-5732)
- Sebastian Major (ORCID: https://orcid.org/0000-0003-0970-1308)
- Sara Simula (ORCID: https://orcid.org/0000-0003-0950-0629)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Linköping University (SE)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Zimmer Biomet (Netherlands) (NL)
- Humboldt-Universität zu Berlin (DE)
- Perimed (Sweden) (SE)
- Centre de Recherche en Neurosciences de Lyon (FR)
- Hospices Civils de Lyon (FR)
- Institut de Neurosciences des Systèmes (FR)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Bernstein Center for Computational Neuroscience Berlin (DE)
- Einstein Center for Neurosciences Berlin (DE)
Publication Details
- Journal
- Stroke
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1161/strokeaha.125.052917
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71