CXCR5 Signals Fine-Tune Dendritic Cell Transcription and Regulate TH2 Development
CXCR5 expressed by cDC2 cells is required for induction of <i>Chi3l1</i>, which in turn promotes the T<sub>H</sub>2 priming capacity of these DCs. These findings provide insight into the actions of CXCR5 and Chi3l1 in helminth infection.
Authors
- Beatriz León (ORCID: https://orcid.org/0000-0002-3793-3854)
- Miranda L. Curtiss (ORCID: https://orcid.org/0000-0001-5118-2279)
- Natalia Ballesteros Benavides
- Frances E. Lund (ORCID: https://orcid.org/0000-0003-3083-1246)
- Christopher D. Scharer (ORCID: https://orcid.org/0000-0001-7716-8504)
- Alexander F. Rosenberg
Institutions
- National Institutes of Health (US)
- Emory University (US)
- University of Alabama at Birmingham (US)
- National Institute of Allergy and Infectious Diseases (US)
Publication Details
- Journal
- Vaccines
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3390/vaccines13090943
- Citations
- 1
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Institutes of Health