CHEMICAL RISK ASSESSMENT METHODS: A COMPREHENSIVE REVIEW AND COMPARATIVE ANALYSIS

Chemical risk assessment is a process that aims to provides information on the probability of adverse effects following chemical exposures. This paper presents a review of the most widely used chemical risk assessment methods, including COSHH Essentials, Institut National de Recherche et de Sécurité (INRS), Chemical Risk Management (CHARM), Stoffenmanager, ECETOC TRA Targeted Risk Assessment, Advanced REACH Tool (ART), New Approach Methodologies (NAM), Critical Task Exposure Screening (CTES), SQCRA Method, Chem-SAM, UOW, and Chemical Health Risk Assessment (CHRA). A comparative analysis highlights their strengths, limitations, application cases, and use cases is also included. Finally are included some recent developments in Artificial Intelligence (AI) applications for chemical risk assessment.