Association of Glucagon-like Peptide-1 Receptor Agonist Use with Complications Following Thoracic and/or Lumbar Spinal Fusion for Degenerative Spine Disease
GLP-1 RA use was linked with reduced perioperative and long-term surgical complications in patients undergoing thoracic and/or lumbar fusions for degenerative spine disease, particularly in those with BMI ≥25. This risk reduction may be attributed to weight loss and/or the systemic metabolic, inflammatory, and vascular benefits of these medications.
Authors
- Peter Gust Passias (ORCID: https://orcid.org/0000-0002-1479-4070)
- Andrew J. Schoenfeld (ORCID: https://orcid.org/0000-0002-3691-1215)
- Lara Langer Cohen (ORCID: https://orcid.org/0000-0003-1412-2001)
- Arman Kishan (ORCID: https://orcid.org/0000-0002-2353-4596)
- Alan H. Daniels (ORCID: https://orcid.org/0000-0001-9597-4139)
- Manjot Singh (ORCID: https://orcid.org/0000-0003-4524-6226)
- Peter Tretiakov (ORCID: https://orcid.org/0000-0002-0580-5129)
- Paweł Jankowski (ORCID: https://orcid.org/0000-0002-3176-8798)
- Nicolas L. Carayannopoulos
- Harmon Singh Khela (ORCID: https://orcid.org/0000-0002-1962-3844)
- Zvipo Chisango (ORCID: https://orcid.org/0009-0008-8977-8375)
- Shaleen Vira
- Kyriakos Chatzis
Institutions
- Rutgers, The State University of New Jersey (US)
- Hoag Memorial Hospital Presbyterian (US)
- Duke University (US)
- Providence College (US)
- Brown University (US)
- Johnson University (US)
- Banner Health (US)
- Massachusetts General Hospital (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Spine
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1097/brs.0000000000005494
- Citations
- 2
- Primary Topic
- Parkinson's Disease and Spinal Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.78