Re-evaluating basophil count as a hematological indicator for bone density: a subgroup analysis from an East Asian population
Basophil count does not appear to be a reliable biomarker for BMD in the general population. However, findings in the higher-BMI subgroup suggest a potential link that warrants further investigation. GPT may hold greater utility as a surrogate marker for bone health in clinical screening. The present findings also highlight the value of publishing negative results and underscore the need for future research in larger and more diverse cohorts.
Authors
- Jun-Jie Hong
- Chao‐Min Cheng (ORCID: https://orcid.org/0000-0002-8644-1960)
- Shu-Wei Huang (ORCID: https://orcid.org/0000-0003-1815-6938)
- Tiffany Wang (ORCID: https://orcid.org/0000-0001-6444-4020)
- Yuli Wang (ORCID: https://orcid.org/0000-0003-0917-5707)
- Kuei-Chen Lee
Institutions
- National Taitung University (TW)
- National Tsing Hua University (TW)
- Hualien Armed Forces General Hospital (TW)
- Powertech Technology (Taiwan) (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fendo.2025.1643760
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hualien Armed Forces General Hospital
- National Tsing Hua University
- Tri-Service General Hospital
- National Science and Technology Council