Predictive Value of Naples Prognostic Score and CONUT Scores for Contrast-induced Acute Kidney Injury After Percutaneous Coronary Intervention in Acute Coronary Syndrome

Objective: Contrast-induced acute kidney injury (CI-AKI) is a significant complication in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI).This study evaluates the predictive value of the Naples prognostic score (NPS) and controlling nutritional status (CONUT) score for CI-AKI risk. Method:The data of 520 ACS patients who underwent PCI between January 2019 and December 2022 were retrospectively analyzed.Patients were stratified by NPS and CONUT scores, based on blood markers including serum albumin, cholesterol, and inflammatory cell counts.CI-AKI was defined as an acute post-contrast renal function decline.Logistic regression and ROC analyses assessed the predictive value of NPS and CONUT scores.Results: CI-AKI occurred in 142 (27.3%) patients.Higher NPS and CONUT scores were significantly associated with increased CI-AKI risk (p<0.001).Multivariate analysis identified NPS and CONUT as independent predictors of CI-AKI (odds ratio: 0.060, p=0.002; odds ratio: 0.442, p=0.008).ROC analysis showed high predictive accuracy (AUC: 0.950 for NPS; AUC: 0.930 for CONUT). Conclusion:NPS and CONUT scores effectively predict CI-AKI risk in ACS patients undergoing PCI.Their routine use may enhance risk stratification and preventive strategies.