Unresectable Primary Enteric‐Type Thymic Adenocarcinoma Treated With <scp>FOLFOX</scp> Chemotherapy: A Case Report

We report the first case of primary enteric-type thymic adenocarcinoma treated at an Australian institution, and the first published case using FOLFOX as frontline systemic therapy in a patient with unresectable primary enteric-type thymic adenocarcinoma. Noting the close molecular resemblance between enteric-type thymic adenocarcinoma and gastrointestinal malignancies, chemotherapy regimens commonly used in the treatment of gastrointestinal cancer may offer a more effective option than standard frontline therapies used in thymic carcinomas for the management of enteric-type thymic adenocarcinoma.

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Publication Details

Journal
Cancer Reports
Published
2025-09-01
DOI
https://doi.org/10.1002/cnr2.70318
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
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article

Unresectable Primary Enteric‐Type Thymic Adenocarcinoma Treated With FOLFOX Chemotherapy: A Case Report

Georgia Bentick, Andrew Mant, Patrick Hosking, Carl He
Cancer Reports
Myasthenia Gravis and Thymoma
article

Unresectable Primary Enteric‐Type Thymic Adenocarcinoma Treated With FOLFOX Chemotherapy: A Case Report

Georgia Bentick, Andrew Mant, Patrick Hosking, Carl He
article en

Abstract

We report the first case of primary enteric-type thymic adenocarcinoma treated at an Australian institution, and the first published case using FOLFOX as frontline systemic therapy in a patient with unresectable primary enteric-type thymic adenocarcinoma. Noting the close molecular resemblance between enteric-type thymic adenocarcinoma and gastrointestinal malignancies, chemotherapy regimens commonly used in the treatment of gastrointestinal cancer may offer a more effective option than standard frontline therapies used in thymic carcinomas for the management of enteric-type thymic adenocarcinoma.

Cancer ReportsVol. 8(9)
Peter MacCallum Cancer Centre (AU), Eastern Health (AU)
Openalex Percentile: Top 66%
Myasthenia Gravis and Thymoma
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