Assessment of docosahexaenoic acid’s preventive efficacy against unconjugated bilirubin neurotoxicity through MRP1 protein expression
In conclusion, data show treatment with DHA protects against neurotoxicity in UCB-induced cellular injury, as it ameliorates alterations in glutamate levels, intracellular Ca<sup>2+</sup>, and ATP by enhancing MRP1 protein expression.
Authors
- Xianyang Liang
- Denghui Wang (ORCID: https://orcid.org/0000-0003-2510-4239)
- Zhen Wang (ORCID: https://orcid.org/0000-0001-7188-5828)
- Qianhao Wang (ORCID: https://orcid.org/0000-0002-1852-4369)
- Jingliang Du
- Ruile Shen
Institutions
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Jining Medical University (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Toxicology Mechanisms and Methods
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1080/15376516.2025.2553853
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00