Recovery effects of various skin lipid components and their structural derivatives on skin barrier damage

This study compares the skin barrier recovery effects of skin lipid components, demonstrating that BA elicits a high skin barrier recovery effect similar to that of CER, which has known efficacy. BA also had an excellent sealing effect through lipid packaging, whereas CER had a combined sealing effect and increased the epidermal thickness and density. These results provide foundational evidence for formulating products that help restore the skin barrier by supplying lipids to the skin surface.

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Publication Details

Journal
International Journal of Cosmetic Science
Published
2025-09-04
DOI
https://doi.org/10.1111/ics.70023
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Recovery effects of various skin lipid components and their structural derivatives on skin barrier damage

Sung Il In, Tae Gyun Kwon, Moonjoo Kim, Jooyoung Oh et al.
International Journal of Cosmetic Science
Advancements in Transdermal Drug Delivery
article

Recovery effects of various skin lipid components and their structural derivatives on skin barrier damage

Sung Il In, Tae Gyun Kwon, Moonjoo Kim, Jooyoung Oh, Sang Gwon Seo, J Ha
article en

Abstract

This study compares the skin barrier recovery effects of skin lipid components, demonstrating that BA elicits a high skin barrier recovery effect similar to that of CER, which has known efficacy. BA also had an excellent sealing effect through lipid packaging, whereas CER had a combined sealing effect and increased the epidermal thickness and density. These results provide foundational evidence for formulating products that help restore the skin barrier by supplying lipids to the skin surface.

International Journal of Cosmetic ScienceVol. 48(1)
LG (South Korea) (KR)
Openalex Percentile: Top 82%
Advancements in Transdermal Drug Delivery
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