Changes in gut microbiota of gallstone mice at different altitudes based on 16S rDNA sequencing
1) Gut microbiota imbalance likely contributes to gallstone formation in mice, and higher microbiota diversity may reduce the incidence of gallstones. 2) The incidence of gallstones is higher at high altitudes than at lower altitudes, possibly due to hypoxic conditions and elevated inflammation levels.
Authors
- Shile Wu
- Wei Gao (ORCID: https://orcid.org/0000-0003-0843-1449)
- Runjie Guo
- Jinjin Sun (ORCID: https://orcid.org/0000-0003-3676-1437)
- Wenjun Zhu (ORCID: https://orcid.org/0009-0007-7754-7126)
- Song Li (ORCID: https://orcid.org/0000-0002-1429-3161)
Institutions
- Qinghai University (CN)
- Qinghai University Affiliated Hospital (CN)
- Qinghai No.3 People's Hospital (CN)
- Qinghai Provincial Peoples Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiomes
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/frmbi.2025.1618718
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00