Serological prevalence of Brucella at the livestockhuman interface in northeast of Deir al-Zor in Syria

Brucellosis, a zoonotic bacterial infection primarily affecting livestock, poses significant health risks to humans, particularly in regions reliant on animal husbandry.This study investigates the seroprevalence of brucellosis among symptomatic individuals in Hajin, located in northeastern Deir al-Zor, Syria, an area where livestock farming is a predominant economic activity.Conducted from March 2023 to May 2024, the cross-sectional study involved the collection of 100 serum samples from patients presenting clinical symptoms suggestive of brucellosis.All samples tested positive for Brucella antibodies via the Serum Agglutination Test (SAT), indicating a critical public health concern within this community.The analysis revealed that 80% of infections were attributed to the consumption of contaminated animal products, primarily unpasteurized dairy items.Demographic data indicated a higher prevalence among males aged 19 to 45, aligning with occupational exposure patterns common in agricultural settings.The study also identified a peak in infection rates during October, likely linked to seasonal agricultural practices.These findings underscore the hyper-endemic nature of brucellosis in Hajin and highlight the urgent need for enhanced public health interventions.Recommendations include the implementation of systematic vaccination programs for livestock, improved surveillance, and educational campaigns focused on the importance of pasteurization and safe food handling practices.The results of this investigation provide critical insights into the epidemiology of brucellosis in northeastern Syria and emphasize the necessity for a comprehensive "One Health" approach to mitigate the disease's impact on both human and animal populations.