Biased Usage of V/D/J Genes and Clonal Diversity in IgG Repertoires Correlates with Disease Activity and Clinical Features in Systemic Autoimmune Diseases
IgG repertoire features reflect disease-related immune perturbations and may serve as potential biomarkers for disease progression, diagnostics and targeted therapies in SAIDs.
Authors
- Yang Song (ORCID: https://orcid.org/0000-0001-7716-9216)
- Ming Zhao (ORCID: https://orcid.org/0000-0002-1320-1093)
- Qianjin Lu (ORCID: https://orcid.org/0000-0002-7749-9618)
- Delong Feng (ORCID: https://orcid.org/0000-0002-0664-0063)
- Qian Wang
- Zhi Hu
Institutions
- Central South University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Chinese Academy of Medical Sciences Dermatology Hospital (CN)
- Institute of Dermatology (TH)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1080/08820139.2025.2550374
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province