Assessment of The Relationship between Heavy Metals and Oxidative Stress in Municipal Workers in The City of Al-Shatraa

Background: Exposure to non-essential heavy metals is a major and growing global threat to environmental pollution. Because of its redox, when antioxidant defenses are insufficient to stop the creation and overproduction of reactive oxygen species (ROS), it can result from redox characteristics. Thus, the present study aimed to observe heavy metal levels and oxidant and antioxidant status. And also to evaluate the relationship between them. Methodology: This study was conducted on a group of workers and municipal controls. During the period between 2023 - 2024. This study includes 40 municipal workers and 40 controls. Patients and controls aged 20- 50 years. Serum PB, Hg, NO, and catalase, SOD, Tf, and CP levels were determined. Results: It was noted that the workers' group's serum components (pb, Hg, NO, and CP) significantly increased (P≤0.05) when compared to the control group. It was discovered that the workers' group's serum concentrations of Tf, SOD, and catalase were significantly lower than those of the control group (P≤0.05). The present study has reported a positive correlation between ( Hg, NO, and CP). While it was found a negative correlation was found between PB ( catalase, SOD, and Tf).