IL17RA and IL21R polymorphisms influence type 1 diabetes predisposition and autoimmune phenotypes
These findings suggest that polymorphisms in IL17RA and IL21R genes may contribute to T1D pathogenesis and modulate the presence of pancreatic and extra-pancreatic autoantibodies.
Authors
- Aritânia Sousa Santos (ORCID: https://orcid.org/0000-0003-4091-5777)
- Cintia Semzezem
- Karla Fabiana Brasil Gomes (ORCID: https://orcid.org/0000-0002-4239-5640)
- Maria Rita Passos‐Bueno (ORCID: https://orcid.org/0000-0002-9248-3008)
- Christophe Chevillard (ORCID: https://orcid.org/0000-0002-5269-8813)
- Amanda Farage Frade-Barros (ORCID: https://orcid.org/0000-0002-9004-8811)
- Maria Elizabeth Rossi da Silva (ORCID: https://orcid.org/0000-0002-7470-0427)
- Pauline Brochet (ORCID: https://orcid.org/0000-0002-5812-0385)
- Edécio Cunha‐Neto (ORCID: https://orcid.org/0000-0002-3699-3345)
- Lindiane Gomes Crisostomo
- Marcia Regina Soares Correia
- Luciano Abreu Brito
Institutions
- Inserm (FR)
- Theories and Approaches of Genomic Complexity (FR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Instituto de Geociencias (ES)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fendo.2025.1620509
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo