Stevia rebaudiana extract (main components: chlorogenic acid and its analogues) as a new safe feed additive: evaluation of acute toxicity, sub chronic toxicity, genotoxicity, and teratogenicity
SREC exhibited low toxicity in both acute and subchronic tests, and no evidence of genotoxicity or teratogenicity was observed. These findings suggest that SREC is safe as a potential feed additive and provide valuable reference data for its safety evaluation.
Authors
- Shusheng Tang (ORCID: https://orcid.org/0000-0003-1860-3582)
- Yuting Li (ORCID: https://orcid.org/0000-0003-2236-6612)
- Dongsheng He (ORCID: https://orcid.org/0000-0002-8503-9099)
- Yajing Li (ORCID: https://orcid.org/0000-0002-7118-4658)
- Ling Fang (ORCID: https://orcid.org/0000-0003-4234-260X)
- Liping Zhu (ORCID: https://orcid.org/0009-0001-0789-2166)
Institutions
- Zoucheng People's Hospital (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fvets.2025.1646665
- Primary Topic
- Biochemical Analysis and Sensing Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China