A Lifelong Battle With Crouzon Syndrome: A Detailed Case Report of Extensive Craniofacial Surgeries and Complex Psychiatric Care

Crouzon syndrome (CS) is a rare genetic disorder characterized by the premature fusion of cranial sutures, leading to distinctive facial features and potential neurological complications. Individuals with craniofacial syndromes often face psychosocial challenges that may increase their vulnerability to mental health issues. This case report details a 55-year-old woman with CS who endured multiple complex surgeries, including brain surgery and Le Fort III advancement osteotomy, during her early years. Having experienced neglect by her biological parents and abuse within her foster care environment, these traumatic experiences likely contributed to her heightened risk for mental health issues. She was later diagnosed with post-traumatic stress disorder and borderline personality disorder and had a history of substance abuse. Despite the prevalence of such psychiatric comorbidities, the intersection between CS and mental health disorders is rarely examined in the literature. This case emphasizes the need for more research and highlights the importance of an integrated care approach to address medical and psychiatric complexities in patients with CS.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-09-04
DOI
https://doi.org/10.7759/cureus.91605
Primary Topic
Craniofacial Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Lifelong Battle With Crouzon Syndrome: A Detailed Case Report of Extensive Craniofacial Surgeries and Complex Psychiatric Care

Mihika Nepal, Luba Leontieva, Soojae Hollowell, Sai Tejaswi Gillela
Cureus
Craniofacial Disorders and Treatments
article

A Lifelong Battle With Crouzon Syndrome: A Detailed Case Report of Extensive Craniofacial Surgeries and Complex Psychiatric Care

Mihika Nepal, Luba Leontieva, Soojae Hollowell, Sai Tejaswi Gillela
article en

Abstract

Crouzon syndrome (CS) is a rare genetic disorder characterized by the premature fusion of cranial sutures, leading to distinctive facial features and potential neurological complications. Individuals with craniofacial syndromes often face psychosocial challenges that may increase their vulnerability to mental health issues. This case report details a 55-year-old woman with CS who endured multiple complex surgeries, including brain surgery and Le Fort III advancement osteotomy, during her early years. Having experienced neglect by her biological parents and abuse within her foster care environment, these traumatic experiences likely contributed to her heightened risk for mental health issues. She was later diagnosed with post-traumatic stress disorder and borderline personality disorder and had a history of substance abuse. Despite the prevalence of such psychiatric comorbidities, the intersection between CS and mental health disorders is rarely examined in the literature. This case emphasizes the need for more research and highlights the importance of an integrated care approach to address medical and psychiatric complexities in patients with CS.

CureusVol. 17(9)
SUNY Upstate Medical University (US), Kakatiya University (IN), Gujarat Cancer Society (IN)
Openalex Percentile: Top 74%
Craniofacial Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

A Lifelong Battle With Crouzon Syndrome: A Detailed Case Report of Extensive Craniofacial Surgeries and Complex Psychiatric Care — Mihika Nepal, Luba Leontieva, et al. · Cureus (2025) | TGRS Research Map | TGRS