Characterization of gut microbiota and metabolites in individuals with constipation-predominant irritable bowel syndrome
Individuals with IBS-C demonstrate gut microbiota dysbiosis, characterized by reduced abundance of specific probiotic species and altered SCFA metabolism, along with potential low-grade inflammatory activity. These findings offer insights into the pathophysiological mechanisms of IBS-C and may inform the development of new therapeutic strategies.
Authors
- Yali Wang (ORCID: https://orcid.org/0000-0002-2948-3400)
- Yanli Cheng (ORCID: https://orcid.org/0000-0001-6904-6275)
- Long Yi (ORCID: https://orcid.org/0009-0009-3100-792X)
- Xiaoqian Xu (ORCID: https://orcid.org/0009-0009-8185-1053)
Institutions
- Beijing Hua Xin Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.3389/fmicb.2025.1617288
- Citations
- 3
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.42