HLA‐A*02:01 Presents Penicillin‐Modified Cysteinylated Peptides for T Cell Recognition
Our study provides evidence that cysteine-penicillin adducts can be accommodated by HLA ligands with the potential to induce T cell-mediated allergic reactions.
Authors
- Patricia T. Illing (ORCID: https://orcid.org/0000-0002-3870-0796)
- Shawn J. R. Goh (ORCID: https://orcid.org/0000-0001-5371-6641)
- Kirti Pandey (ORCID: https://orcid.org/0000-0003-0799-6376)
- Robyn E. O’Hehir (ORCID: https://orcid.org/0000-0002-3489-7595)
- Nicole A. Mifsud
- Kirsten Deckert
- Robert Puy (ORCID: https://orcid.org/0000-0001-7001-6313)
- Katherine E. Scull (ORCID: https://orcid.org/0000-0003-4042-7685)
- Mohammadreza Dorvash (ORCID: https://orcid.org/0000-0002-1935-9625)
- Anthony W. Purcell (ORCID: https://orcid.org/0000-0003-0532-8331)
- Hong Xing Lu
Institutions
- Discovery Institute (US)
- Alfred Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Allergy
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1111/all.70025
- Citations
- 1
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Monash University
- Australian Research Data Commons
- Medical Research Council
- National Health and Medical Research Council
- Faculty of Medicine, Nursing and Health Sciences, Monash University
- Leibniz-Gemeinschaft
- Institute of Infection and Immunity