Epigenome-wide DNA methylation profiling in aneurysmal subarachnoid hemorrhage and delayed ischemic neurologic deficit: a prospective observational study
Our prospective observational EWAS identified significant DNA methylation changes in the blood cells and demonstrated a functional link to specific biological processes in aSAH. Further validation studies are necessary to confirm our findings.
Authors
- Marcin Sawicki (ORCID: https://orcid.org/0000-0003-0129-2343)
- Dagmara Lisman (ORCID: https://orcid.org/0000-0003-2876-5665)
- Leszek Sagan (ORCID: https://orcid.org/0000-0001-5366-1070)
- Wojciech Poncyljusz (ORCID: https://orcid.org/0000-0002-5173-5635)
- Tomasz Kazimierz Wojdacz (ORCID: https://orcid.org/0000-0001-6003-2432)
- Olga Taryma‐Leśniak (ORCID: https://orcid.org/0000-0002-1161-5399)
- Dominik Taterra (ORCID: https://orcid.org/0000-0001-5135-6750)
- Konrad Jarosz (ORCID: https://orcid.org/0000-0001-5444-5150)
- Tomasz Klepinowski (ORCID: https://orcid.org/0000-0003-4806-2094)
- Jan Bińkowski (ORCID: https://orcid.org/0000-0003-2374-2907)
- Andrzej Ossowski (ORCID: https://orcid.org/0000-0002-6819-1638)
- Patrycja Kamila Przybylowicz (ORCID: https://orcid.org/0009-0004-0009-4710)
- Kajetan Łątka (ORCID: https://orcid.org/0000-0002-4230-4489)
Institutions
- Jagiellonian University (PL)
- St. Hedwig-Krankenhaus (DE)
- Pomeranian Medical University (PL)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1097/js9.0000000000003324
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00