Liquid chromatography coupled to mass spectrometry for steroid hormones analysis: issues and solutions in sample preparation and method development
Current work presents main aspects of the application of liquid chromatography in combination with low- and high-resolution mass spectrometry to an analysis of steroid hormones. Advantages and challenges of both targeted and untargeted analysis are shown together with the most popular approaches to the associated sample preparation. Among emerging approaches, first applications of isotope ratio mass spectrometry in combination with liquid chromatography for the analysis of steroid hormones for doping control purposes are presented and discussed.
Authors
- I. I. Podolskiy
- Sergey Girel (ORCID: https://orcid.org/0000-0002-8165-537X)
- Elina Gashimova (ORCID: https://orcid.org/0000-0002-9618-7580)
- Sanka N. Atapattu (ORCID: https://orcid.org/0000-0003-2647-2228)
- Yu‐Qi Feng (ORCID: https://orcid.org/0000-0003-1107-5385)
- А. З. Темердашев (ORCID: https://orcid.org/0000-0002-8048-4740)
- Quan‐Fei Zhu (ORCID: https://orcid.org/0000-0003-1539-0227)
- T. Yu. Malitskaya
Publication Details
- Journal
- Journal of Chromatography Open
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1016/j.jcoa.2025.100250
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Russian Science Foundation