Genetic and clinical risk factors for anti-tuberculosis drug-induced liver injury: insights from a prospective cohort study in central Ethiopia

DILI is a common early complication of TBT in Ethiopian patients. Assessment of sociodemographic factors and TE before TBT may help identify high-risk individuals and offers a pragmatic approach for DILI management in resource-limited settings.

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Publication Details

Journal
Infection
Published
2025-09-04
DOI
https://doi.org/10.1007/s15010-025-02632-7
Citations
1
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
1.56
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article

Genetic and clinical risk factors for anti-tuberculosis drug-induced liver injury: insights from a prospective cohort study in central Ethiopia

Tom Luedde, André Fuchs, Kristina Behnke, Tamara Nordmann et al.
1 citations
Infection
Drug-Induced Hepatotoxicity and Protection
1.56
article

Genetic and clinical risk factors for anti-tuberculosis drug-induced liver injury: insights from a prospective cohort study in central Ethiopia

Tom Luedde, André Fuchs, Kristina Behnke, Tamara Nordmann, Torsten Feldt, Tafese Beyene Tufa, Caroline Klindt, Carola Dröge, Björn‐Erik Ole Jensen, Andreas Schönfeld, Frieder Pfäfflin, Million Getachew Mesfun, Kirsten Alexandra Eberhardt, Verena Keitel, H Orth
article en
1 citations

Abstract

DILI is a common early complication of TBT in Ethiopian patients. Assessment of sociodemographic factors and TE before TBT may help identify high-risk individuals and offers a pragmatic approach for DILI management in resource-limited settings.

InfectionVol. 53(6)
Universität Hamburg (DE), Heidelberg University (DE), Research Institute for Tropical Medicine (PH), University Hospital Heidelberg (DE), Humboldt-Universität zu Berlin (DE), Düsseldorf University Hospital (DE), University Medical Center Hamburg-Eppendorf (DE), Asossa University (ET), University Medical Centre Mannheim (DE), Arsi University, Heinrich Heine University Düsseldorf (DE), University of Duisburg-Essen (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE), Bernhard Nocht Institute for Tropical Medicine (DE), Otto-von-Guericke-Universität Magdeburg (DE)
Openalex Percentile: Top 16%
Drug-Induced Hepatotoxicity and Protection
1.56
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