Classification of small blue round cell tumors by integrating peptide and N-glycan mass imaging spectrometric profiles

Peptide and N-glycan MSI has huge potential and is a promising tool to discriminate different SBRCT entities. Combining mass spectrometry imaging data from peptides and N-glycans even enhanced classification performance. At the same time, the results underline the importance of an accurate spatial mapping to create such integrated data sets.

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Publication Details

Journal
Analytica Chimica Acta
Published
2025-09-04
DOI
https://doi.org/10.1016/j.aca.2025.344614
Primary Topic
Glycosylation and Glycoproteins Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Classification of small blue round cell tumors by integrating peptide and N-glycan mass imaging spectrometric profiles

Alice Ly, Kristina Schwamborn, Juliana Pereira Lopes Gonçalves, Christine Bollwein et al.
Analytica Chimica Acta
Glycosylation and Glycoproteins Research
article

Classification of small blue round cell tumors by integrating peptide and N-glycan mass imaging spectrometric profiles

Alice Ly, Kristina Schwamborn, Juliana Pereira Lopes Gonçalves, Christine Bollwein, Nathan Heath Patterson, Naomi O'Sullivan
article en

Abstract

Peptide and N-glycan MSI has huge potential and is a promising tool to discriminate different SBRCT entities. Combining mass spectrometry imaging data from peptides and N-glycans even enhanced classification performance. At the same time, the results underline the importance of an accurate spatial mapping to create such integrated data sets.

Analytica Chimica ActaVol. 1376
Technical University of Munich (DE)
Deutsche Forschungsgemeinschaft
Openalex Percentile: Top 79%
Glycosylation and Glycoproteins Research
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