Head-down position after reperfusion improves cerebral ischaemic injury in rat
This is the first study to demonstrate the cerebroprotective effect of HDP -20° with 1 hour duration immediately after reperfusion in MCAO/R model rats, which involved inhibition of neuroinflammation and apoptosis as well as protection of BBB.
Authors
- Qiong Wu (ORCID: https://orcid.org/0000-0002-0749-7529)
- Dawei Chen (ORCID: https://orcid.org/0000-0002-7486-1992)
- Nannan Zhang
- Yina Zhang (ORCID: https://orcid.org/0000-0003-0921-0058)
- Ji‐Ru Cai
Institutions
- General Hospital of Shenyang Military Region (CN)
- Northeastern University (CN)
Publication Details
- Journal
- Stroke and Vascular Neurology
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1136/svn-2025-004409
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China