bFGF rescues dysfunctional properties of adipose-derived stem cells from individuals with type 2 diabetes by modulating their miRNA profile

Preconditioning T2DM ASCs with bFGF alters their miRNA profile, enhancing cell proliferation and their vascular remodelling potential. This strategy could improve the therapeutic utility of T2DM ASCs.

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Publication Details

Journal
Diabetologia
Published
2025-09-04
DOI
https://doi.org/10.1007/s00125-025-06533-0
Citations
1
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
1.63

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article

bFGF rescues dysfunctional properties of adipose-derived stem cells from individuals with type 2 diabetes by modulating their miRNA profile

Esther Peña, Lina Badimón, Anna Civit-Urgell, Fabrizio Moscatiello et al.
1 citations
Diabetologia
Mesenchymal stem cell research
1.63
article

bFGF rescues dysfunctional properties of adipose-derived stem cells from individuals with type 2 diabetes by modulating their miRNA profile

Esther Peña, Lina Badimón, Anna Civit-Urgell, Fabrizio Moscatiello, Maria Teresa Béjar, Gemma Arderiu, Gemma Vilahur
article en
1 citations

Abstract

Preconditioning T2DM ASCs with bFGF alters their miRNA profile, enhancing cell proliferation and their vascular remodelling potential. This strategy could improve the therapeutic utility of T2DM ASCs.

DiabetologiaVol. 68(12)
Universitat de Vic - Universitat Central de Catalunya (ES), Wellcome/MRC Cambridge Stem Cell Institute (GB), University of Cambridge (GB), Instituto de Salud Carlos III (ES), Hospital de Sant Pau (ES), Centro de Investigación Biomédica en Red de Salud Mental (ES), Hospital Quirón Teknon (ES), Centro de Investigación Biomédica en Red (ES), Centro de Investigación Biomédica en Red de Cáncer (ES), Institut de Recerca Sant Pau (ES), Universitat de Barcelona (ES)
Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya, Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares, Dirección para el Desarrollo de la Ciencia y el Conocimiento, Instituto de Salud Carlos III, European Regional Development Fund
Openalex Percentile: Top 14%
Mesenchymal stem cell research
1.63
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bFGF rescues dysfunctional properties of adipose-derived stem cells from individuals with type 2 diabetes by modulating their miRNA profile — Esther Peña, Lina Badimón, et al. · Diabetologia (2025) | TGRS Research Map | TGRS