Effect of lipid-lowering medications on oxidized phospholipids in individuals with elevated LIPOPROTEIN(a)
Among patients with elevated Lp(a), both high-intensity statin and add-on ezetimibe significantly increased OxPL-apoB and OxPL-apo(a) levels, while significantly decreased OxPL-PLG levels. Add-on PCSK9i had no significant effect on OxPLs levels. The clinical implications of these findings should be further explored.
Authors
- Amalia Despoina Koutsogianni
- Fotios Barkas (ORCID: https://orcid.org/0000-0002-5940-6895)
- Constantinos C. Tellis (ORCID: https://orcid.org/0000-0002-3959-1544)
- Alexandros D. Tselepis (ORCID: https://orcid.org/0000-0002-5854-2385)
- Georgé Liamis (ORCID: https://orcid.org/0000-0003-1522-8318)
- Evangelos Liberopoulos (ORCID: https://orcid.org/0000-0002-7162-3323)
- Sotirios Tsimikas (ORCID: https://orcid.org/0000-0001-9834-9494)
Institutions
- University of Ioannina (GR)
- University of California San Diego (US)
- Laiko General Hospital of Athens (GR)
Publication Details
- Journal
- Atherosclerosis Plus
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.athplu.2025.09.003
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01